Seventy percent of immunity is gut-based, with billions of lymphocytes making up the G.A.L.T or gut-associated lymphoid tissue. These immune cells are in the gut wall, dense areas like payers patches, crypts, and mesenteric lymph nodes.
With a healthy microbiome, you can have good immune modulation regulation of immunity. With an unstable microbiome, you can get inflammation and immune dysregulation. These impacts on immunity can be acute but in many of our animals can also be chronic.
With our gut microbiome linked to our lungs, skin, brain, and other organ function. We need to do everything we can to achieve homeostasis in the gut microbiome.
Finally, we must remember the microbiome is affected by many factors like nutrition, stress, the environment, or other toxins. We are always trying to promote both diversity and stability in the microbiome. It is a complex interaction between pathogens and essential commensals in the gut.